Selected Publications

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Solís EJ, Pandey JP, Zheng X, Jin DX, Gupta PB, Airoldi EM, Pincus D, Denic V. (2016). Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis. Molecular Cell; Jun 15 [Epub ahead of print].

Kamber R., Shoemaker C., Denic V. (2015). A molecular switch for selective autophagosome formation. Autophagy; Nov 2;11(11):2132-2133.

Denic V. (2015). Advice to a young scientist (by someone who doesn’t know how to give it). Molecular Biology of the CellNov 1;26(21):3681-3.

Kamber R., Shoemaker C., Denic V. (2015). Receptor-Bound Target of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase. Molecular Cell; Aug 6;59(3):372-81.

Wang F., Chan C., Weir N. R., Denic V. (2014). The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase. Nature; Aug 28;512(7515):441-4.

Denic V, Dötsch V, Sinning I. (2013). ER Targeting and Insertion of Tail-Anchored Membrane Proteins by the GET Pathway. Cold Spring Harb Perspect Biol; Aug 1;5(8):a013334.

Denic V. (2012). A portrait of the GET pathway as a surprisingly complicated young man. Trends in Biochemical Sciences; Oct;37(10):411-7.

Wang F., Whynot A., Tung M., Denic V. (2011). The Mechanism of Tail-Anchored Protein Insertion into the ER Membrane. Molecular Cell; 43, 738-750.

Stefer S., Reitz S., Wang F., Wild K., Pang YY., Schwarz D, Bomke J, Hein C, Löhr F, Bernhard F, Denic V*., Dötsch V*., Sinning I*. Structural Basis for Tail-Anchored Membrane Protein Biogenesis by the Get3-Receptor Complex. Science; 2011 Aug. 5; 333(6043): 758-762.   *co-corresponding authors.

Denic V. (2011). No Country for Old Misfolded Glycoproteins. Molecular Cell; 42, 715-717.

Wang F., Brown E. C., Mak G., Zhuang J., Denic V. (2010). A Chaperone Cascade Sorts Proteins for Post-Translational Membrane Insertion into the ER. Molecular Cell; 40, 159-171

 

Other publications (in chronological order):

1.  Bhamidipati, A., Denic, V., Quan, E. M., Weissman, J. S. (2005). Exploration of the Topological Requirements of ERAD Identifies Yos9p as a Lectin Sensor of Misfolded Glycoproteins in the ER lumen. Molecular Cell; 19, 741-751.

2.  Schuldiner, M., Collins, S. R., Thompson, N. J., Denic, V., Bhamidipati, A., et al. (2005). Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile. Cell; 123, 507-519.

3.  Denic V., Quan E. M., Weissman, J. S. (2006). A Luminal Surveillance Complex that Selects Misfolded Glycoproteins for Endoplasmic Reticulum-Associated Degradation. Cell; 126, 349-359.

4.  Denic V., Weissman J. S. (2007). A Molecular Caliper Mechanism for Determining Very Long-Chain Fatty Acid Length. Cell; 130, 663-677.

5.  Schuldiner M.,* Metz J., Schmid V., Denic V.* et al. (2008). The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER. Cell; 134, 634-645. (*co-first author)

6.  Quan, E. M.,  Kamiya, Y., Kamiya, D., Denic, V.,  Weibezahn, J., Kato, K., Weissman, J. S. (2008). Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation. Molecular Cell; 32, 870-877.

7.  Jonikas, M. C., Collins, S. R., Denic, V., Oh, E., Quan, E. M., Schmid, V., Weibezahn, J., Schwappach, B., Walter, P., Weissman, J. S., Schuldiner, M. The Anatomy of a Cellular Folding Compartment. Science; 2009 Mar 27; 323(5922): 1693-7.

8. Hu J., Li J., Qian X., Denic V., Sha B. The Crystal Structures of Yeast Get3 Suggest a Mechanism for Tail-Anchored Protein Membrane Insertion PLoS One. 2009 Nov. 30; 4(11)e8061.